Bruce A. Watkins, PhDProfessorPhone: 860-486-0866 Education
Research ActivitiesThe major aim of our research is to determine the amounts and balance of dietary polyunsaturated fatty acids for optimal human nutrition and health, and characterize their roles in bone biology and muscle disuse atrophy. The first goal is to understand the role of DHA and EPA on muscle and bone communications. The research is directed at characterizing how specific polyunsaturated fatty acids influence the endocannabinoid signaling pathways in muscle and bone. These experiments investigate actions in osteoblast cell cultures and various animal models. Studies that examine polyunsaturated fatty acids and gene modulation of osteoblast function/differentiation and expression of gene products associated with bone formation are of primary interest. The second goal is to determine the interactions of nutrients and flavonoids on bone formation. Affiliations
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